Uterine Cancer

Endometrial cancer is the most prevalent gynecologic cancer in the US. It commonly arises from the lining of the uterus but can also arise from the muscle of the uterus.

Symptoms include vaginal bleeding after menopause or abnormal bleeding patterns before menopause. This can include bleeding that is heavier during menstrual periods or bleeding between periods. In most cases, a biopsy from the lining of your uterus is recommended to evaluate if a cancer is present.

Cancers from the lining of the uterus (carcinomas) are often categorized as endometrioid, serous, or clear cell cancer. Treatment typically involves surgery with removal of the uterus, fallopian tubes, and ovaries, but can also involve chemotherapy and radiation.

Cancers can also arise from the muscle of the uterus. These are called sarcomas and include leiomyosarcoma and endometrial stromal sarcoma. Carcinosarcomas share characteristics of sarcomas and carcinomas. Sarcomas are also treated with surgery and/or chemotherapy and radiation depending on the stage at diagnosis.